Intensive Ambulance-Delivered Blood- Pressure Reduction in Hyperacute Stroke   Li, Y. Lin, J. Yang, C.S. Anderson, C. Chen, F. Liu, L. Billot, Q. Li, X. Chen, X. Liu, X. Ren, C. Zhang, P. Xu, L. Wu, F. Wang, D. Qiu, M. Jiang, Y. Peng, C. Li, Y. Huang, X. Zhao, J. Liang, Y. Wang, X. Wu, Xiaoyun Xu, G. Chen, D. Huang, Y. Zhang, L. Zuo, G. Ma, Y. Yang, J. Hao, Xiahong Xu, X. Xiong, Y. Tang, Y. Guo, J. Yu, S. Li, S. He, F. Mao, Q. Tan, S. Tan, N. Yu, R. Xu, M. Sun, B. Li, J. Guo, L. Liu, H. Liu, M. Ouyang, L. Si, H. Arima, P.M. Bath, G.A. Ford, T. Robinson, E.C. Sandset, J.L. Saver, N. Sprigg, H.B. van der Worp, and L. Song, for the INTERACT4 investigators*                                               N Engl J Med 2024;390:1862-72. May 16 2024

Background                                                                                                        Treatment of acute stroke, before a distinction can be made between ischemic and haemorrhagic types, is challenging. Whether very early blood-pressure control in the ambulance improves outcomes among patients with undifferentiated acute stroke is uncertain